鹿児島大学 学術研究院 医歯学域 歯学系 歯科応用薬理学分野 准教授 富田和男


プロフィール

  19742月生まれ。茨城県北茨城市出身。

  野口雨情さん (「七つの子」や「赤い靴」を作詞した人、英世さんや聡一さんではありません) と同郷です。
  埼玉大学   理学部 生体制御学科を卒業後、いろいろありまして・・・。
  鹿児島大学 歯学部 生体機能制御学講座 歯科応用薬理学分野にお世話になることになりました。
  いかつい体つきをしていますが、寂しがりです。なので、声をかけてあげると喜びます。
  まだまだ若輩者でわからないことだらけですが、一生懸命がんばろうと思いますのでよろしくお願いします。


略歴

  平成13  3月 埼玉大学大学院博士後期課程修了 博士(理学)取得
  平成13  4月 独立行政法人放射線医学総合研究所 重点研究支援協力員
  平成1312月 鹿児島大学 歯学部 助手
  平成2811月 鹿児島大学 学術研究院 医歯学研究域 歯学系 歯科応用薬理学分野 助教
  令和  2  4
月 鹿児島大学 学術研究院 医歯学研究域 歯学系 歯科応用薬理学分野 講師
  令和  6  8月 鹿児島大学 学術研究院 医歯学研究域 歯学系 歯科応用薬理学分野 准教授


研究テーマ


  ・がんの放射線・薬剤耐性メカニズムの解析
  ・漢方薬の効果について
  ・破骨細胞分化
  ・ラット神経細胞に対する酸化ストレスとその制御
  ・酸化ストレスにおける細胞障害
 


受賞


  2019-21年度 歯学部ベストリサーチャー賞
  2018年度   歯学部同窓会奨励賞
  2005年     野井倉武憲賞
  2002年     The Oxigen Society Travel Award
 


主な研究業績


 (原著論文・総説)


 Kitanaka N, Arai K, Takehara K, Hall FS, Tomita K, Igarashi K, Sato T, Uhl GR, Kitanaka J.
  Opioid receptor antagonists reduce motivated wheel running behavior in mice.
  Behavioural Pharmacology. 35 114-121 2024 .

 Kuwahara Y, Kitamura M, Tomita K, Muraoka T, Chida T, Roudkenar MH, Roushandeh AM, Sato T, Kamijo K, Kurimasa A.
  Radiation-induced Cell Death: relevance to cancer cell radioresistance.
  Radiation Environment and Medicine. 13 1‐9 2024 .

 Tomita K*, Oohara Y, Igarashi K, Kitanaka J, Kitanaka N, Tanaka K, Roudkenar MH, Roushandeh AM, Sugimura M, Sato T. 
  Kamishoyosan and Kamikihito protect against decreased KCC2 expression induced by the P. gingivalis lipopolysaccharide treatment in PC-12 cells and improve behavioral abnormalities in male mice.
  Heliyon. 9 e22784 2023 .

 Tomita K*, Kuwahara Y, Igarashi K, Kitanaka J, Kitanaka N, Takashi Y, Tanaka K, Roudkenar MH, Roushandeh AM Kurimasa A, Nishitani Y, Sato T.
  Therapeutic potential for KCC2-targeted neurological diseases.
  Japanese Dental Science Review 59 431-438 2023 .

 Igarashi K, Kuchiiwa S, Kuchiiwa T, Tomita K, Sato T.
  Comparative data on emotional (psychotic) aggressive biting behavior in mice of ddY strain measured by using two devices; Aggressive response meter and powerlab-compatible type aggressive response meter.
  Data in Brief. 109231 2023 .

 Bamshad C, Roudkenar MH, Abedinzade M, Yousefzadeh Chabok S, Pourmohammadi-Bejarpasi Z, Najafi-Ghalehlou N, Sato T, Tomita K, Jahanian-Najafabadi A, Feizkhah A, Roushandeh AR.
  Human umbilical cord-derived mesenchymal stem cells-harvested mitochondrial transplantation improved motor function in TBI models through rescuing neuronal cells from apoptosis and alleviating astrogliosis and microglia activation.
  Int Immunopharmacol 118 110106 2023 .

 Nikoo A, Roudkenar MH, Sato T, Kuwahara Y, Tomita K, Pourmohammadi-Bejarpasi Z, Najafi-Ghalehlou N, Roushandeh AR.
  Mitochondrial transfer in PC-3 cells fingerprinted in ferroptosis sensitivity: a brand new approach targeting cancer metabolism.
  Human Cell 36 (4) 2023 .

 Kitanaka J#, Kitanaka N#, Tomita K#, Hall FS, Igarashi K, Uhl GR, Sato T.
  Glycogen Synthase Kinase-3 Inhibitors Block Morphine-Induced Locomotor Activation, Straub Tail, and Depression of Rearing in Mice Via a Possible Central Action.
  Neurochem Res 48(7) 2230-2240. 2023.

  Tomita K, Indo HP, Sato T, Tangpong J, Majima HJ.
  Development of a sensitive double TaqMan Probe-based qPCR Angle-Degree method to detect mutation frequencies.
  Mitochondrion 70 1-7 2023.

 Kuwahara Y#, Tomita K#*, Roudkenar MH, Roushandeh AM, Sato T, Kurimasa A.
 The reversibility of cancer radioresistance: a novel potential way to identify factors contributing to tumor radioresistance.
  Human Cell 36(3) 963-971. 2023

 Bamshad C, Najafi-Ghalehlou N, Pourmohammadi-Bejarpasi Z, Tomita K, Kuwahara Y, Sato T, Feizkhah A, Roushnadeh AM, Roudkenar MH.
 Mitochondria: how eminent in ageing and neurodegenerative disorders?
  Human Cell 36 41-61 2023.

 Hasegawa K, Saga R, Ohuchi K, Kuwahara Y, Tomita K, Okumura K, Sato T, Fukumoto M, Tsuruga E, Hosokawa Y.
 4-Methylumebelliferone Enhances Radiosensitizing Effects of Radioresistant Oral Squamous Cell Carcinoma Cells via Hyaluronan Synthase 3 Suppression.
  Cells 11 3780 2022.

 Hosseinalizadeh H, Roudkenar MH, Roushandeh AM, Kuwahara Y, Tomita K*, Sato T.
 Natural killer cell immunotherapy in glioblastoma.
  Discov Oncol 13 113 2022.

 Valashedi MR, Roushandeh AM, Tomita K, Kuwahara Y, Pourmohammadi-Bejarpasi Z, Kozani PS, Sato T, Roudkenar MH.
 CRISPR/Cas9-mediated knockout of Lcn2 in human breast cancer cell line MDA-MB-231 ameliorates erastin-mediated ferroptosis and increases cisplatin vulnerability.
  Life Sci 304 120704 2022.

 Igarashi K, Iwai H, Tanaka K, Kuwahara Y, Kitanaka J, Kitanaka N, Kurimasa A, Tomita K, Sato T.
 Neuroprotective effect of oxytocin on cognitive dysfunction, DNA damage, and intracellular chloride disturbance in young mice after cranial irradiation.
  BBRC 612 1-7 2022.

 Kitanaka N, Hall FS, Tanaka K, Tomita K, Igarashi K, Nishiyama N, Sato T, Uhl GR, Kitanaka J.
 Are histamine H3 antagonists the definitive treatment for acute methamphetamine intoxication?
  Curr Drug Res Rev 14 162-170 2022.

 Valashedi MR, Bamshad C, Najafi-Ghalehlou N, Nikoo A, Tomita K, Kuwahara Y, Sato T, Roushandeh AM, Roudkenar MH.
 Non-coding RNAs in ferroptotic cancer cell death pathway: meet the new masters.
  Human Cell 35 972-994 2022.

 Fukui R, Saga R, Matsuya Y, Tomita K, Kuwahara Y, Ohuchi K, Sato T, Okumura K, Date H, Fukumoto M, Hosokawa Y.
 Tumor radioresistance caused by radiation-induced changes of stem-like cell content and sub-lethal damage repair capability.
  Sci Rep 12 1056 2022.

 Tomita K*, Yamanishi-Taira S, Igarashi K, Oogai U, Kuwahara Y, Roudkenar MH, Roushandeh AM, Miyawaki S, Kurimasa A, Sato T.
 Oxytocin ameliorates KCC2 decrease induced by oral bacteria-derived LPS that affect rat primary cultured cells and PC-12 cells.
  Peptides 150 170734 2022.

 Valashedi MR, Nikoo A, Najafi-Ghalehlou N, Tomita K, Kuwahara Y, Sato T, Roushandeh AM, Roudkenar MH.
 Pharmacological Targeting of Ferroptosis in Cancer Treatment.
  Curr Cancer Drug Targets 22 115-132 2022 .

 Kuwahara Y#, Tomita K#*, Roudkenar MH, Roushandeh AM, Urushihara Y, Igarashi K, Kurimasa A, Sato T.
 Decreased mitochondrial membrane potential is an indicator of radioresistant cancer cells.
  Life Sci 286 120051 2021.

 Valashedi MR, Najafi-Ghalehlou N, Nikoo A, Bamshad C, Tomita K, Kuwahara Y, Sato T, Roushandeh AM, Roudkenar MH.
 Cashing in on ferroptosis against tumor cells: Usher in the next chapter.
  Life Sci 285 11995 2021.

 Kitanaka N, Hall FS, Kobori S, Kushihara S, Oyama H, Sasaoka Y, Takechi M, Tanaka KI, Tomita K, Igarashi K, Nishiyama N, Sato T, Uhl GR, Kitanaka J.
 Metoprine, a histamine N-methyltransferase inhibitor, attenuates methamphetamine-induced hyperlocomotion via activation of histaminergic neurotransmission in mice.
  Pharmacol Biochem Behav 209 173257 2021.

 Tomita K*, Kuwahara Y, Igarashi K, Roudkenar MH, Roushandeh AM, Kurimasa A, Sato T.
 Mitochondrial Dysfunction in Diseases, Longevity, and Treatment Resistance: Tuning Mitochondria Function as a Therapeutic Strategy.
  Genes 12(9) 1348 2021.

 Tomita K*, Nagasawa T, Kuwahara Y, Torii S, Igarashi K, Roudkenar MH, Roushandeh AM, Kurimasa A, Sato T.
 MiR-7-5p is Involved in Ferroptosis Signaling and Radioresistance Thru the Generation of ROS in Radioresistant HeLa and SAS Cell Lines.
  Int J Mol Sci 22 8300 2021.

 Igarashi K, Kuchiiwa T, Kuchiiwa S, Iwai H, Tomita K, Sato T.
 Kamishoyosan (a Japanese traditional herbal formula), which effectively reduces the aggressive biting behavior of male and female mice, and potential regulation through increase of Tph1, Tph2, and Esr2 mRNA levels.
  Brain Res 1768 147580 2021.

 Niiro A, Ohno SN, Yamagata KA, Yamagata K, Tomita K, Kuramoto E, Oda Y, Nakamura TJ, Nakamura W, Sugimura M.
 Diurnal Variation in Trigeminal Pain Sensitivity in Mice.
  Front Neurosci 15 703440 2021.

 Kuwahara Y, Tomita K*, Roudkenar MH, Roushandeh AM, Urushihara Y, Igarashi K, Nagasawa T, Kurimasa A, Fukumoto M, Sato T.
 The Effects of Hydrogen Peroxide and/or Radiation on the Survival of Clinically Relevant Radioresistant Cells.
  Technol Cancer Res Treat 19 2020.

 Takashi Y#, Tomita K#, Kuwahara Y, Roudkenar MH, Roushandeh AM, Igarashi K, Nagasawa T, Nishitani Y, Sato T.
 Mitochondrial dysfunction promotes aquaporin expression that controls hydrogen peroxide permeability and ferroptosis.
  Free Radical Biology & Medicine 161 60-70 2020.

 Pourmohammadi-Bejarpasi Z, Roushandeh AM, Saberi A, Kheirandish-Rostami M, Toosi SMR, Jahanian-Najafabadi A, Tomita K, Kuwahara Y, Sato T, Roudkenar MH.
 Mesenchymal stem cells-derived mitochondria transplantation mitigates I/R-induced injury, abolishes I/R-induced apoptosis, and restores motor function in acute ischemia stroke rat model.
  Brain research bulletin 165 70-80 2020.

 Roushandeh AM#, Tomita K#, Kuwahara Y, Jahanian-Najafabadi A, Igarashi K, Roudkenar MH, Sato T.
 Transfer of healty fibroblast-derived mitochondria to HeLa ρ0 and SAS ρ0 cells recovers the proliferation capabilities of these cancer cells under conventional culture medium, but increase their sensitivity to cisplatin-induced apoptotic death.
  Molecular Biology Reports 47(6) 4401-4411 2020.

 Kheirandish-Rostami M, Roudkenar MH, Jahanian-Najafabadi A, Tomita K, Kuwahara Y, Sato T, Roushandeh AM.
 Mitochondrial characteristics contribute to proliferation and migration potency of MDA-MB-231 cancer cells and their response to cisplatin treatment.
  Life Sci. 244 117339 2020.

 Tomita K, Fukumoto M, Itoh K, Kuwahara Y,Igarashi K, Nagasawa T, Suzuki M, Kurimasa A, Sato T.
  MiR-7-5p is a key factor that controls radioresistance via intracellular Fe2+ content in clinically relevant radioresistant cells.
  BBRC 518(4) 712-718 2019.

 Tomita K#*,Takashi Y#, Ouchi U, Kuwahara Y,Igarashi K, Nagasawa T, Nabika H, Kurimasa A, Fukumoto M, Nishitani Y, Sato T.
  Lipid peroxidation increases hydrogen peroxide permeability leading to cell death in cancer cell lines that lack mtDNA.
  Cancer Sci 110(9) 2856-2866 2019.

 Kuwahara Y, Tomita K, Takahashi S, Urushihara Y, Saito Y, Roudkenar MH, Roushandeh AM, Sato T, Kurimasa A, Fukumoto M.

 Mitochondrial dysfunction in cross-resistance of clinically relevant radioresistant cells to X-rays and docetaxel.

 J Cancer Sci & Therapy 10(12) 379-383 2018.

 

 Kuwahara Y, Tomita K, Urushihara Y, Sato T, Kurimasa A, Fukumoto M. Sato T.
 Association between radiation-induced cell death and clinically relevant radioresistance.
 Histochemistry and Cell Biology 150(6) 649-659 2018.

 Tomita K, Kuwahara Y, Takashi Y, Igarashi K, Nagasawa T, Nabika H, Kurimasa A, Fukumoto M, Nishitani Y, Sato T.
 Clinically Relevant Radioresistant Cells Exhibit Resistance to H2O2 by Decreasing Internal H2O2 and Lipid Peroxidation.
 Tumor biology 40(9) 2018.

 Takashi Y, Tomita K, Kuwahara Y, Nabika H, Igarashi K, Nagasawa T, Kurimasa A, Fukumoto M, Nishitani Y, Sato T.
 Data on the aquaporin gene expression differences among ρ0, clinically relevant radioresistant, and the parental cells of human cervical cancer and human tongue squamous cell carcinoma.
 Data in Brief 20 402-410 2018.

 Kuwahara Y, Roudkenar MH, Urushihara Y, Saito Y, Tomita K, Roushandeh AM, Sato T, Kurimasa A, Fukumoto M.
 Clinically relevant radioresistant cells: a simple model to understand cancer radioresistance.
 Med Mol Morphol 50(4) 195-204 2017.

 Kuwahara Y, Roudkenar MH, Urushihara Y, Saito Y, Tomita K, Roushandeh AM, Sato T, Kurimasa A, Fukumoto M.
 X-Ray Induced Mutation Frequency at the Hypoxanthine Phosphoribosyltransferase Locus in Clinically Relevant Radioresistant Cells.
 International Journal of Medical Physics Clinical Engineering and Radiation Oncology 6 377-391 2017.

 Furukawa M, Tsukahara T, Tomita K, Iwai H, Sonomura T, Miyawaki S, Sato T.
 Neonatal maternal separation delays the GABA excitatory-to-inhibitory functional switch by inhibiting KCC2 expression.
 BBRC 493(3) 1243-1249 2017.

  Tomita K, Kuwahara Y, Takashi Y, Tsukahara T, kurimasa A, Fukumoto M, Nishitani Y, Sato T.
  Sensitivity of Mitochondrial DNA Depleted ρ0 Cells to H2O2 Depends on the Plasma Membrane Status.
  BBRC 490(2) 330-335 2017.

  Nandakumar A, Uwatoko F, Yamamoto M, Tomita K, Majima H, Akiba S, Koriyma C.
  Radiation-induced Epstein-Barr virus reactivation in gastric cancer cells with latent EBV infection.
  Tumor Biology 39(7) 2017.

  Indo HP, Majima HJ, Terada M, Suenaga S, Tomita K, Yamada S, Higashibata A, Ishioka N, Kanekura T, Nonaka I, Haukins CL, Davis MJ, St Clair DK, Mukai C.
  Changes in mitochondrial homeostasis and redox status in astronauts following long stays in space.
  Scientific Reports 6 39015 2016.
 
  Masuhara M, Tsukahara T, Tomita K, Furukawa M, Miyawaki S, Sato T.
  A relation between osteoclastogenesis inhibition and membrane-type estrogen receptor GPR30.
  Biochemistry and Biophysics Reports 8 389-394 2016.

  Maeda K, Kawai H, Sanada M, Terashima T, Ogawa N, Idehara R, Makiishi T, Yasuda H, Sato S, Hoshi K, Yahikozawa H, Nishi K, Itoh Y, Ogasawara K, Tomita K, Indo H, Majima HJ.
  Similar clinical phenotype and segregation of mitochondrial 3243A>G mutation in two pairs of monozygotic twins.
  JAMA Neurology 73(8) 990-993 2016.

  Indo HP, Tomiyoshi T, Suenaga S, Tomita K, Suzuki H, Masuda D, Terada M, Ishioka N, Gusev O, Cornette R, Okuda T, Mukai C, Majima HJ.
  MnSOD downregulation induced by extremely low 0.1 mGy single and fractionated X-rays and microgravity treatment in human neuroblastoma cell line, NB-1.
  Journal of Clinical Biochemistry and Nutrition 57(2) 98-104 2015.

  Indo HP, Davidson M, Yen H-C, Suenaga S, Tomita K, Nishii T, Higuchi M, Koga Y, Ozawa T, Majima HJ.
  Evidence of ROS generation by mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage.
  Mitochondrion 7(1-2) 106-118 2007.

  Ijiri K, Tsuruga H, Sakakima H, Tomita K, Taniguchi N, Shimoonoda K, Komiya S, Goldring MB, Majima HJ, Matsuyama T.
  Increased expression of humanin peptide in diffuse-type pigmented villonodular synovitis: implication of its mitochondrial abnormality.
  Ann Rheum Dis 64(6) 816-823 2005.

  Hirai F, Motoori S, Kakinuma S, Tomita K, Indo HP, Kato H, Yamaguchi T, Yen H-C, St.Clair DK, Nagano T, Ozawa T, Saisho H and Majima HJ.
  Mitochondrial Signal Lacking Manganese Superoxide Dismutase Failed to Prevent Cell Death by Reoxygenation following Hypoxia in a Human Pancreatic Cancer Cell Line, KP4.
  Antioxidant & Redox Signaling 6(3) 523-535 2004.

  Tomita K, Yamasu K, Suyemitsu T.
  Role of syndecan in the elongation of postoral arms in sea urchin larva.
  Development Growth and differentiation 44(1) 45-53 2002.

  Tomita K, Yamasu K, Suyemitsu T.
  Cloning and characterization of the cDNA for syndecan core protein in sea urchin embryo.
  Development Growth and differentiation 42(5) 449-458 2000.

  Hirate Y, Tomita K, Yamamoto S, Kobari K, Uemura I, Yamasu K, Suyemitsu T.
  Association of the sea urchin EGF-related peptide, EGIP-D, with fasciclin I-related ECM proteins from the sea urchin Anthocidaris crassispina.
  Development Growth and differentiation 41(4) 483-494 1999.

  *: コレスポ #: equal contribution


 (日本語の総説・著書・その他)


  橋 将世、桑原 義和、富田 和男、五十嵐 健人、上野 誠、宮崎 貴文、杉本 義仁、栗政 明弘、佐藤 友昭
 ナノ銀の生物効果について.
  東北医科薬科大学研究誌  2023 in press .


  富田和男、桑原義和、五十嵐健人、高裕子、長澤大成、山西沙祐里、西谷佳浩、漆原佑介、宮脇正一、栗政明弘、福本学、佐藤友昭
 細胞内鉄動態と酸化ストレス抵抗性 .
  東北医科薬科大学研究誌 66 25-31 2019.


  富田和男、五十嵐健人、見芳野、高橋将世、佐藤友昭
 がんとその治療抵抗性におけるミトコンドリアの役割について .
  鹿児島県歯科医師会報誌 8-9 9-11 2023.


  桑原義和、富田和男、千田千佳、漆原佑介、上条桂樹、佐藤友昭、福本学、栗政明弘
 細胞の変化から見た放射線で誘発される細胞死.
  月刊 細胞 「THE CELL」 臨時増刊号  53 41-45 2021 .


  五十嵐健人、富田和男、桑原義和、栗政明弘、佐藤友昭
 オキシトシンの精神作用と精神疾患への応用に向けたアプローチ.
  東北医科薬科大学研究誌 67 41-45 2020 .


  富田和男、桑原義和、五十嵐健人、福本学、佐藤友昭
 放射線耐性におけるミトコンドリアの役割.
  放射線生物研究 55 370-383 2020 .


  富田和男、桑原義和、五十嵐健人、高裕子、長澤大成、山西沙祐里、西谷佳浩、漆原佑介、宮脇正一、栗政明弘、福本学、佐藤友昭
 細胞内鉄動態と酸化ストレス抵抗性 .
  東北医科薬科大学研究誌 66 25-31 2019.

 

  桑原義和、富田和男、高畠貴志、漆原佑介、五十嵐健人、佐藤友昭、栗政明弘、福本学昭
 臨床的放射線耐性細胞のこれまでとこれから .
  東北医科薬科大学研究誌 66 19-24 2019.

 

  五十嵐健人、富田和男、桑原義和、山西沙祐里、古川みなみ、宮脇正一、栗政明弘、佐藤友昭
 ストレス関連病態におけるGABA応答障害の関与 .
  東北医科薬科大学研究誌 65 7-10 2018.

 

 
桑原義和、富田和男、北原秀治、五十嵐健人、漆原佑介、斎藤陽平、佐藤友昭、栗政明弘、福本学
 標準的放射線療法に抵抗性を示すがん細胞の不思議な性質.
  東北医科薬科大学研究誌 65 11-19 2018.

 

  Furukawa M, Yamanishi S, Igarashi K, Tomita K, Miyawaki S, Sato T.
  Delay of GABA switch due to early ? life stress leads to developmental disorder.
  Atlas of Science 2018.

 

  Takashi Y, Tomita K, Kuwahara Y, kurimasa A, Fukumoto M, Nishitani Y, Sato T.
  Oxidative stress sensitivity of cancer cells could be altered by plasma membrane status.
  Atlas of Science 2018

 

  桑原義和、富田和男、漆原佑介、齋藤陽平、佐藤友昭、栗政明弘、福本学
  2Gy/日のX線分割照射に抵抗性を示すがん細胞の樹立と解析.
  東北医科薬科大学研究誌 64 39-48 2017.

 

  富田和男、桑原義和、高裕子、並河英紀、西谷佳浩、漆原佑介、山西沙祐里、古川みなみ、宮脇正一、栗政明弘、福本学、佐藤友昭
  ミトコンドリア障害細胞における酸化ストレス感受性と細胞膜動態.  .
  東北医科薬科大学研究誌 64 49-55 2017.

  桑原義和、鈴木正敏、漆原佑介、齋藤陽平、山本由美、富田和男、佐藤友昭、山本文彦、栗政明弘、福本学
  放射線で誘発される細胞死:アポトーシス、オートファジー、ネクロプトーシス
  東北医科薬科大学研究誌 63 63-70 2016.
 
  馬嶋秀行、佐藤強志、末永重明、犬童寛子、河野一典、川畑義裕、富田和男
  顎顔面放射線学分野における研究活動報告
  鹿児島大学紀要 33 99-100 2013.

  Majima HJ, Indo HP, Suzuki H, Tomita K, Ishioka N, Shimazu T, Yano S, Tanigaki F, Nagamatsu A, Masuda D, Imaoka A, Shibata Y, Abiko Y, Kishida S, Minobe E, Kameyama M.
  Space Experiments of Human Neuron Cells on ISS, Kibo.
  Space Utiliz Res 28 199-200 2012.

  Suenaga S, Indo HP, Tomita K, Ijiri K, Komiyama S, Matsuyama T, Yen H-C, Higuchi M, Matsui H, Ozawa T, Majima HJ.
  Nitric- and Oxidative Mitochondria Related Cell Death by Cytokines and its Prevention by Estrogen in Estrogen Receptor Expressed Rheumatoid Arthritis Synovial Fibroblasts.
  Nitric Oxide Biology and Chemistry 22(S2) S85 2010.

  Majima HJ, Indo HP, Tomita K, Iwashita Y, Suzuki H, Masuda D, Shimazu T, Tanigaki F, Umemura S, Yano S, Fukui K, Higashibata A, Yamazaki TQ, Kameyama M, Suenaga S, Sato T, Yen H-C, Gusev O, Okuda T, Matsui H, Ozawa T, Ishioka N.
 Bio-assessment of risk in long-term manned space exploration- cell death factors in space radiation and/or microgravity: a review -.
 Biol Sci Space 23(2) 43-53 2009.

  犬童寛子、Sriburee Sompong富田和男、馬嶋秀行
  ケルセチン処置におけるラット正常胃粘膜上皮細胞及び由来癌細胞のMnSOD効果の差異
  G. I. Research 17(4) 102-103 2009.

  Majima HJ, Indo HP, Tomita K, Iwashita Y, Suzuki H, Masuda D, Shimazu T, Higashibata A, Izumi R, Hasegawa Y, Ishioka N.
 Gene expression profiles of human neuron-like cells exposed to cosmic rays.
 Space Utiliz Res 25 37-38 2009.

  馬嶋秀行、犬童寛子、富田和男、松井裕史、小澤俊彦
  ミトコンドリア・アポトーシスと酸化ストレス
  酸化ストレスの医学、吉川敏一監修、内藤裕二、豊國伸哉編集、診断と治療社、81-87 2008.

  犬童寛子、富田和男、馬嶋秀行
 
MnSODによるラット胃癌細胞 RGK1 における酸化ストレス誘導タンパク発現抑制調節
 
G. I. Research 16(4) 90-91 2008.

  犬童寛子、富田和男、松井裕史、小澤俊彦、馬嶋秀行
  放射線感受性におけるミトコンドリアの役割
  放射線生物研究
42(4) 416-427 2007.

  Majima HJ, Indo HP, Tomita K, Suenaga S, Motoori S, Kato H, Yen H-C, Ozawa T.
  Intracellular oxidative stress caused by ionizing radiation
  Oxidative Stress, Disease and Cancer, ed. Singh K., Imperial College Press, London, UK, 61-83 2006.


  富田和男、岩下洋一朗、犬童寛子、末永重明、佐藤強志、馬嶋秀行.
  低線量X 線照射による正常神経細胞への影響
  第46 回日本歯科放射線学会総会 "野井倉武憲賞 (学会賞)" 受賞 2005.

  下小野田一騎、井尻幸成、小宮節郎、富田和男、馬嶋秀行
 
Humanin
  関節外科 23(8) 84-85 2004.

  Indo H, Davidson M, Koga Y, Tomita K, Yen H-C, Setsukinai K, Urano Y, Nagano T, Ozawa T, Majima HJ.
  Microscopic Evidence of ROS Generation from Mitochondria in DNA Damaged Cells.
  Free Rad Bio Med. 35(S1) S118 2003.

  Tomita K, Iwashita Y, Indo H, Hayata I, Ozawa T, Majima HJ.
  Effect of low dose X-ray irradiation on human neuronal progenitor cell.
  Free Rad Bio Med. 33(S1), S429 2002. "Travel award"

  馬嶋秀行、山口千鶴、柿沼志津子、本居成淳、平井太、山口洋子、富田和男、小澤俊彦
  放射線障害に対する細胞内ミトコンドリアの役割
  新ミトコンドリア学
283-288 共立出版 2001.


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